Walter J Koch Selected Research

beta-Adrenergic Receptor Kinases

9/2005	Acute ischemic cardiac dysfunction is attenuated via gene transfer of a peptide inhibitor of the beta-adrenergic receptor kinase (betaARK1).
10/2004	Catheter-mediated delivery of adenoviral vectors expressing beta-adrenergic receptor kinase C-terminus inhibits intimal hyperplasia and luminal stenosis in rabbit iliac arteries.
8/2004	Genetic and phenotypic targeting of beta-adrenergic signaling in heart failure.
3/2004	Right ventricular targeted gene transfer of a beta-adrenergic receptor kinase inhibitor improves ventricular performance after pulmonary artery banding.
1/2004	In vivo adenoviral-mediated gene transfer of the beta ARKct to study the role of G beta gamma in arterial restenosis.
10/2003	The beta-adrenergic receptor kinase in heart failure.
8/2003	Phosphorylation of G protein-coupled receptors: GPCR kinases in heart disease.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Walter J Koch Research Topics

Disease

126	Heart Failure 01/2022 - 01/2000
37	Myocardial Infarction 01/2022 - 12/2002
26	Myocardial Ischemia (Ischemic Heart Diseases) 01/2022 - 11/2002
25	Hypertrophy 01/2022 - 01/2002
24	Cardiomegaly (Heart Hypertrophy) 01/2022 - 08/2002
22	Ischemia 01/2022 - 02/2002
16	Infarction (Infarctions) 01/2022 - 08/2004
15	Cardiomyopathies (Cardiomyopathy) 01/2022 - 06/2002
14	Reperfusion Injury 02/2019 - 02/2002
12	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 01/2000
10	Hypertension (High Blood Pressure) 01/2017 - 07/2002
9	Left Ventricular Dysfunction 02/2019 - 12/2004
8	Inflammation (Inflammations) 12/2020 - 01/2010
7	Hypoxia (Hypoxemia) 01/2022 - 06/2012
7	Fibrosis (Cirrhosis) 01/2022 - 08/2014
6	Neoplasms (Cancer) 01/2022 - 09/2003
6	Heart Diseases (Heart Disease) 12/2015 - 08/2003
6	Hyperplasia 08/2007 - 01/2000
5	Atherosclerosis 01/2017 - 01/2013
5	Ventricular Remodeling 02/2014 - 03/2004
4	Wounds and Injuries (Trauma) 01/2022 - 05/2008
4	Disease Progression 04/2015 - 09/2006
4	Ventricular Dysfunction 01/2011 - 11/2002
3	Sepsis (Septicemia) 01/2020 - 02/2013
2	Ischemic Stroke 12/2020 - 10/2003
2	Cicatrix (Scar) 01/2020 - 01/2019
2	Endotoxemia 01/2020 - 01/2019
2	Body Weight (Weight, Body) 01/2019 - 11/2007
2	Hyperaldosteronism (Conn Syndrome) 01/2019 - 12/2014

Drug/Important Bio-Agent (IBA)

28	Phosphotransferases (Kinase)IBA 01/2021 - 01/2002
23	Adrenergic Agents (Adrenergic Drugs)IBA 01/2018 - 01/2000
23	beta Adrenergic ReceptorsIBA 01/2009 - 01/2002
22	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2022 - 12/2004
22	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2021 - 08/2003
21	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2003
20	Peptides (Polypeptides)IBA 01/2021 - 03/2002
18	G-Protein-Coupled Receptor Kinase 2IBA 01/2017 - 09/2003
14	beta-adrenergic receptor kinase inhibitory peptideIBA 10/2010 - 01/2000
12	CatecholaminesIBA 01/2021 - 10/2006
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 05/2007
8	AldosteroneIBA 01/2019 - 01/2009
8	CalciumIBA 01/2019 - 09/2004
7	G-Protein-Coupled Receptor Kinase 5IBA 01/2022 - 04/2012
7	AdiponectinIBA 09/2014 - 02/2010
7	beta-Adrenergic Receptor KinasesIBA 09/2005 - 08/2003
6	G-Protein-Coupled Receptor KinasesIBA 10/2018 - 06/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2016 - 05/2007
5	Erythropoietin FDA Link 01/2022 - 10/2003
5	salicylhydroxamic acid (SHAM)IBA 01/2022 - 05/2008
5	Pharmaceutical PreparationsIBA 01/2019 - 01/2000
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 02/2002
5	Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA 01/2017 - 09/2003
5	Insulin (Novolin)FDA Link 12/2015 - 05/2008
5	S100A1 proteinIBA 07/2011 - 01/2002
4	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2022 - 05/2008
4	Adenosine (Adenocard)FDA LinkGeneric 01/2022 - 11/2006
4	Messenger RNA (mRNA)IBA 01/2020 - 03/2007
4	Interleukin-10 (Interleukin 10)IBA 01/2020 - 12/2015
4	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2020 - 02/2014
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 04/2013
4	Protein Isoforms (Isoforms)IBA 01/2018 - 08/2006
4	Caveolin 3IBA 11/2015 - 03/2011
3	Biological ProductsIBA 01/2020 - 08/2013
3	LigandsIBA 01/2019 - 09/2003
3	Glucose (Dextrose)FDA LinkGeneric 12/2018 - 08/2008
3	Phenylephrine (Neo-Synephrine)FDA LinkGeneric 01/2018 - 11/2002
3	MicroRNAs (MicroRNA)IBA 09/2017 - 08/2014
3	Angiotensin IIIBA 04/2016 - 11/2002
3	Neurotransmitter Agents (Neurotransmitter)IBA 02/2014 - 01/2002
3	Transcription Factors (Transcription Factor)IBA 12/2013 - 06/2002
2	erucylphosphocholineIBA 01/2022 - 01/2020
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 01/2002
2	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2022 - 04/2018
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2022 - 09/2008
2	Mitogen-Activated Protein KinasesIBA 01/2021 - 12/2005
2	Neutralizing AntibodiesIBA 12/2020 - 01/2019
2	Peptide Hydrolases (Proteases)FDA Link 12/2020 - 01/2005
2	CaspasesIBA 12/2020 - 01/2005
2	Circular RNAIBA 01/2020 - 01/2019
2	Therapeutic UsesIBA 01/2020 - 10/2010
2	Monoclonal AntibodiesIBA 01/2020 - 02/2019
2	Angiotensin Receptor AntagonistsIBA 10/2019 - 12/2014
2	Complementary DNA (cDNA)IBA 01/2019 - 08/2006
2	CytokinesIBA 01/2019 - 02/2013
2	Doxycycline (Periostat)FDA LinkGeneric 01/2019 - 08/2011
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019 - 09/2017
2	Superoxides (Superoxide)IBA 01/2018 - 01/2013
2	Adenosine Triphosphatases (ATPase)IBA 11/2017 - 03/2011
2	Paroxetine (Paxil)FDA LinkGeneric 10/2017 - 03/2015
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2017 - 01/2002
2	Vasopressins (Vasopressin)IBA 11/2016 - 08/2011
2	Tamoxifen FDA LinkGeneric 10/2016 - 08/2008
2	Hormones (Hormone)IBA 04/2016 - 01/2002
2	Small Interfering RNA (siRNA)IBA 03/2016 - 01/2013

Therapy/Procedure

33	Therapeutics 01/2022 - 07/2003
11	Ligation 01/2022 - 07/2002
3	Heart Transplantation (Grafting, Heart) 05/2008 - 03/2004
2	Transplantation 11/2021 - 12/2015
2	Injections 01/2021 - 01/2018
2	Punctures 01/2019 - 01/2019